Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI

Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI

Introduction: Acute kidney injury (AKI) is one of the most common causes of organ failure in critically ill patients. Following AKI, the canonical pro-inflammatory cytokine interleukin-1β (IL-1β) is released predominantly from activated myeloid cells and binds to the interleukin-1 receptor R1 (IL-1R...

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Bibliographic Details
Main Authors: Yanting Chen, Xiaohan Lu, Raeann L. Whitney, Yu Li, Matthew J. Robson, Randy D. Blakely, Jen-Tsan Chi, Steven D. Crowley, Jamie R. Privratsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
acute kidney injury
myeloid cells
cytokines
interleukin-1
ischemia-reperfusion
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1366259/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2024.1366259/full

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