Alpha-Synuclein and the Endolysosomal System in Parkinson’s Disease: Guilty by Association

Abnormal accumulation of the protein α- synuclein (α-syn) into proteinaceous inclusions called Lewy bodies (LB) is the neuropathological hallmark of Parkinson’s disease (PD) and related disorders. Interestingly, a growing body of evidence suggests that LB are also composed of other cellular componen...

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Bibliographic Details
Main Authors: Maxime Teixeira, Razan Sheta, Walid Idi, Abid Oueslati
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/9/1333