RCAN1-mediated calcineurin inhibition as a target for cancer therapy

Abstract Cancer is the leading cause of mortality worldwide. Regulator of calcineurin 1 (RCAN1), as a patent endogenous inhibitor of calcineurin, plays crucial roles in the pathogenesis of cancers. Except for hypopharyngeal and laryngopharynx cancer, high expression of RCAN1 inhibits tumor progressi...

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Bibliographic Details
Main Authors: Mengyi Lao, Xiaozhen Zhang, Hanshen Yang, Xueli Bai, Tingbo Liang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-022-00492-7