Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents

Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents

We synthesized five novel tryptamine derivatives characterized by the presence of an azelayl chain or of a 1,1,1-trichloroethyl group, in turn connected to another heterocyclic scaffold. The combination of tryptamin-, 1,1,1-trichloroethyl- and 2-aminopyrimidinyl- moieties produced compound <b>...

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Bibliographic Details
Main Authors: Giorgia Simonetti, Carla Boga, Joseph Durante, Gabriele Micheletti, Dario Telese, Paolo Caruana, Andrea Ghelli Luserna di Rorà, Fabio Mantellini, Samantha Bruno, Giovanni Martinelli, Natalia Calonghi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
cancer
tryptamine
leukemias
chloral
pyrimidine
Online Access:https://www.mdpi.com/1420-3049/26/3/683

Internet

https://www.mdpi.com/1420-3049/26/3/683

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