Ribonucleic Acid Sequencing Reveals the Upregulation and Resolution of Inflammation and Extracellular Matrix Remodeling in Lidocaine-Treated Human Acute Monocytic Leukemia Cell Line THP-1

Ribonucleic Acid Sequencing Reveals the Upregulation and Resolution of Inflammation and Extracellular Matrix Remodeling in Lidocaine-Treated Human Acute Monocytic Leukemia Cell Line THP-1

Lidocaine, a local anesthetic widely used in dentistry, is esteemed for its efficacy and safety. Recent research reveals its additional role in modulating the immune system, and particularly in reducing inflammation crucial for protecting tooth-supporting tissues. Notably, monocytes and macrophages,...

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Bibliographic Details
Main Authors: Sheng-Wei Feng, Wei-Chun Lin, I-Ta Lee, Sheng-Dean Luo, Ching-Shuen Wang
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biomedicines
Subjects:
local anesthetic
anti-inflammation
macrophage polarization
resolution of inflammation
wound healing
Online Access:https://www.mdpi.com/2227-9059/12/3/509

Internet

https://www.mdpi.com/2227-9059/12/3/509

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