Deconstructing cold-induced brown adipocyte neogenesis in mice

Cold exposure triggers neogenesis in classic interscapular brown adipose tissue (iBAT) that involves activation of β1-adrenergic receptors, proliferation of PDGFRA+ adipose tissue stromal cells (ASCs), and recruitment of immune cells whose phenotypes are presently unknown. Single-cell RNA-sequencing...

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Bibliographic Details
Main Authors: Rayanne B Burl, Elizabeth Ann Rondini, Hongguang Wei, Roger Pique-Regi, James G Granneman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/80167