Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes

<p>Abstract</p> <p>Background</p> <p>Prolonged alcohol consumption is a significant co-factor in the progression of chronic viral infections including hepatitis C and HIV, which are both single-stranded RNA viruses. Toll like receptor 8 (TLR8), a pattern recognition rec...

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Bibliographic Details
Main Authors: Kodys Karen, Bala Shashi, Pang Maoyin, Catalano Donna, Szabo Gyongyi
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Immunology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2172/12/55