The human viral challenge model: accelerating the evaluation of respiratory antivirals, vaccines and novel diagnostics

Abstract The Human Viral Challenge (HVC) model has, for many decades, helped in the understanding of respiratory viruses and their role in disease pathogenesis. In a controlled setting using small numbers of volunteers removed from community exposure to other infections, this experimental model enab...

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Bibliographic Details
Main Authors: Rob Lambkin-Williams, Nicolas Noulin, Alex Mann, Andrew Catchpole, Anthony S. Gilbert
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-018-0784-1