Investigating selection on viruses: a statistical alignment approach

<p>Abstract</p> <p>Background</p> <p>Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading frame can bias our estimates of neutral mutation rates in another rea...

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Bibliographic Details
Main Authors: Lunter Gerton, Mailund Thomas, de Groot Saskia, Hein Jotun
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/304