Comprehensive statistical inference of the clonal structure of cancer from multiple biopsies

Comprehensive statistical inference of the clonal structure of cancer from multiple biopsies

Abstract A comprehensive characterization of tumor genetic heterogeneity is critical for understanding how cancers evolve and escape treatment. Although many algorithms have been developed for capturing tumor heterogeneity, they are designed for analyzing either a single type of genomic aberration o...

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Bibliographic Details
Main Authors: Jie Liu, John T. Halloran, Jeffrey A. Bilmes, Riza M. Daza, Choli Lee, Elisabeth M. Mahen, Donna Prunkard, Chaozhong Song, Sibel Blau, Michael O. Dorschner, Vijayakrishna K. Gadi, Jay Shendure, C. Anthony Blau, William S. Noble
Format: Article
Language:English
Published: Nature Portfolio 2017-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-16813-4

Internet

https://doi.org/10.1038/s41598-017-16813-4

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