The Development of Lipid-Based Sorafenib Granules to Enhance the Oral Absorption of Sorafenib

Sorafenib (SFN) is an anticancer multi-kinase inhibitor with great therapeutic potential. However, SFN has low aqueous solubility, which limits its oral absorption. Lipids and surfactants have the potential to improve the solubility of water-insoluble drugs. The aim of this study is thus to develop...

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Bibliographic Details
Main Authors: Jaylen C. Mans, Xiaowei Dong
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/12/2691