Hydrogen bond-enhanced nanogel delivery system for potential intranasal therapy of Parkinson's disease

Parkinson's disease (PD) is a severe neurodegenerative disease with a high incidence in the elderly and is mainly treated by drugs. The blood–brain barrier (BBB) limits the entry of oral neuroactive drugs to the brain, reducing drug concentration and affecting the treatment of PD. Nanotechnolog...

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Bibliographic Details
Main Authors: Yi-Bing Chen, Tao Qiao, Yan-Qiu Wang, Yuan-Lu Cui, Qiang-Song Wang
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S026412752200363X