Disrupting the SKN-1 homeostat: mechanistic insights and phenotypic outcomes

The mechanisms that govern maintenance of cellular homeostasis are crucial to the lifespan and healthspan of all living systems. As an organism ages, there is a gradual decline in cellular homeostasis that leads to senescence and death. As an organism lives into advanced age, the cells within will a...

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Bibliographic Details
Main Authors: Chris D. Turner, Carmen M. Ramos, Sean P. Curran
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2024.1369740/full