Amelioration of Cognitive and Behavioral Deficits after Traumatic Brain Injury in Coagulation Factor XII Deficient Mice

Amelioration of Cognitive and Behavioral Deficits after Traumatic Brain Injury in Coagulation Factor XII Deficient Mice

Based on recent findings that show that depletion of factor XII (FXII) leads to better posttraumatic neurological recovery, we studied the effect of FXII-deficiency on post-traumatic cognitive and behavioral outcomes in female and male mice. In agreement with our previous findings, neurological defi...

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Bibliographic Details
Main Authors: Christian Stetter, Simon Lopez-Caperuchipi, Sarah Hopp-Krämer, Michael Bieber, Christoph Kleinschnitz, Anna-Leena Sirén, Christiane Albert-Weißenberger
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
closed head injury
contact-kinin system
object recognition memory
IntelliCage
Crespi effect
stress
Online Access:https://www.mdpi.com/1422-0067/22/9/4855

Internet

https://www.mdpi.com/1422-0067/22/9/4855

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