Fatty acid transport protein-5 (FATP5) deficiency enhances hepatocellular carcinoma progression and metastasis by reprogramming cellular energy metabolism and regulating the AMPK-mTOR signaling pathway

Fatty acid transport protein-5 (FATP5) deficiency enhances hepatocellular carcinoma progression and metastasis by reprogramming cellular energy metabolism and regulating the AMPK-mTOR signaling pathway

Abstract Aberrant lipid metabolism is an essential feature of hepatocellular carcinoma (HCC). Fatty acid transport protein-5 (FATP5) is highly expressed in the liver and is involved in the fatty acid transport pathway. However, the potential role of FATP5 in the pathogenesis of HCC remains largely u...

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Bibliographic Details
Main Authors: Ming-Da Wang, Nan-Ya Wang, Hui-Lu Zhang, Li-Yang Sun, Qiu-Ran Xu, Lei Liang, Chao Li, Dong-Sheng Huang, Hong Zhu, Tian Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-021-00364-5

Internet

https://doi.org/10.1038/s41389-021-00364-5

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