S100B Inhibition Attenuates Intestinal Damage and Diarrhea Severity During Clostridioides difficile Infection by Modulating Inflammatory Response

S100B Inhibition Attenuates Intestinal Damage and Diarrhea Severity During Clostridioides difficile Infection by Modulating Inflammatory Response

The involvement of the enteric nervous system, which is a source of S100B, in Clostridioides difficile (C. difficile) infection (CDI) is poorly understood although intestinal motility dysfunctions are known to occur following infection. Here, we investigated the role of S100B in CDI and examined the...

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Bibliographic Details
Main Authors: Deiziane V. S. Costa, Vivaldo Moura-Neto, David T. Bolick, Richard L. Guerrant, Jibraan A. Fawad, Jae H. Shin, Pedro H. Q. S. Medeiros, Solanka E. Ledwaba, Glynis L. Kolling, Conceição S. Martins, Venkat Venkataraman, Cirle A. Warren, Gerly A. C. Brito
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Clostridioides difficile
S100B
inflammation
diarrhea
enteric glia
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.739874/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.739874/full

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