Neuroimmune semaphorins as costimulatory molecules and beyond

Abstract Several neuronal guidance proteins, known as semaphorin molecules, function in the immune system. This dual tissue performance has led to them being defined as “neuroimmune semaphorins”. They have been shown to regulate T cell activation by serving as costimulatory molecules. Similar to cla...

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Bibliographic Details
Main Author: Svetlana P. Chapoval
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Molecular Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s10020-018-0014-9