Pellino-1 Regulates the Responses of the Airway to Viral Infection

Pellino-1 Regulates the Responses of the Airway to Viral Infection

Exposure to respiratory pathogens is a leading cause of exacerbations of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). Pellino-1 is an E3 ubiquitin ligase known to regulate virally-induced inflammation. We wished to determine the role of Pellino-1 in the host respo...

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Bibliographic Details
Main Authors: Elizabeth K. Marsh, Elizabeth C. Prestwich, Lynne Williams, Amber R. Hart, Clare F. Muir, Lisa C. Parker, Marnix R. Jonker, Irene H. Heijink, Wim Timens, Mark Fife, Tracy Hussell, Marc B. Hershenson, J. Kelley Bentley, Shao-Cong Sun, Ben S. Barksby, Lee A. Borthwick, James P. Stewart, Ian Sabroe, David H. Dockrell, Helen M. Marriott
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Pellino-1
influenza A virus
rhinovirus
COPD
asthma
airway epithelia
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00456/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00456/full

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