Somatostatin-SSTR3-GSK3 modulates human T-cell responses by inhibiting OXPHOS

IntroductionSomatostatin (SST) is a peptide hormone primarily synthesized in the digestive and nervous systems. While its impact on the endocrine system is well-established, accumulating evidence suggests a crucial role for SST and its analogues in modulating immune responses. Despite this, the prec...

Full description

Bibliographic Details
Main Authors: Bo Zhang, Huiru Feng, Hui Lin, Rui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1322670/full