Aerobic Exercise Modulates Proteomic Profiles in Gastrocnemius Muscle of <i>db/db</i> Mice, Ameliorating Sarcopenia

Aerobic Exercise Modulates Proteomic Profiles in Gastrocnemius Muscle of <i>db/db</i> Mice, Ameliorating Sarcopenia

Type-2 diabetes mellitus (T2DM)-induced sarcopenia is intertwined with diminished insulin sensitivity and extracellular matrix (ECM) remodeling in skeletal muscle and other organs. Physical activities such as aerobic exercise play a crucial role in regulating blood glucose levels, insulin sensitivit...

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Bibliographic Details
Main Authors: Yen-Chun Huang, Monika Renuka Sanotra, Chi-Chang Huang, Yi-Ju Hsu, Chen-Chung Liao
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Life
Subjects:
aerobic exercise
<i>db/db</i> mice
ECM remodeling
gastrocnemius muscle
metabolic pathways
muscle regeneration
Online Access:https://www.mdpi.com/2075-1729/14/3/412

Internet

https://www.mdpi.com/2075-1729/14/3/412

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