Differences in Sirtuin Regulation in Response to Calorie Restriction in Cryptococcus neoformans

Cryptococcus neoformans successfully replicates in low glucose in infected patients. In the serotype A strain, H99, growth in this condition prolongs lifespan regulated by SIR2, and can be modulated with SIR2-specific drugs. Previous studies show that lifespan modulation of a cryptococcal population...

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Bibliographic Details
Main Authors: Tejas Bouklas, Lindsey Masone, Bettina C. Fries
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Journal of Fungi
Subjects:
Online Access:http://www.mdpi.com/2309-608X/4/1/26