Sensitive and specific quantification of antisense oligonucleotides using probe alteration-linked self-assembly reaction technology

Quantitative bioanalysis is essential when establishing pharmacokinetic properties during the drug development process. To overcome challenges of sensitivity, specificity and process complexity associated with the conventional analysis of antisense oligonucleotides (ASOs), a new approach to nonenzym...

Full description

Bibliographic Details
Main Authors: Masako Osawa, Takurou Akiya, Funa Ogawa, Takao Suzuki, Masaki Yamagami, Tadashi Umemoto, Akira Ideno
Format: Article
Language:English
Published: Taylor & Francis Group 2023-07-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/btn-2023-0005