Sensitive and specific quantification of antisense oligonucleotides using probe alteration-linked self-assembly reaction technology
Quantitative bioanalysis is essential when establishing pharmacokinetic properties during the drug development process. To overcome challenges of sensitivity, specificity and process complexity associated with the conventional analysis of antisense oligonucleotides (ASOs), a new approach to nonenzym...
Main Authors: | Masako Osawa, Takurou Akiya, Funa Ogawa, Takao Suzuki, Masaki Yamagami, Tadashi Umemoto, Akira Ideno |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-07-01
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Series: | BioTechniques |
Subjects: | |
Online Access: | https://www.future-science.com/doi/10.2144/btn-2023-0005 |
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