Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect

Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect

Advanced urothelial bladder cancer (UBC) patients are tagged by a dismal prognosis and high mortality rates, mostly due to their poor response to standard-of-care platinum-based therapy. Mediators of chemoresistance are not fully elucidated. This work aimed to study the metabolic profile of advanced...

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Bibliographic Details
Main Authors: Julieta Afonso, Catarina Barbosa-Matos, Ricardo Silvestre, Joana Pereira-Vieira, Samuel Martins Gonçalves, Camille Mendes-Alves, Pier Parpot, Joana Pinto, Ângela Carapito, Paula Guedes de Pinho, Lúcio Santos, Adhemar Longatto-Filho, Fátima Baltazar
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Cancers
Subjects:
urothelial bladder cancer
cisplatin resistance
Warburg effect
glucose
lactate
lipid metabolism
Online Access:https://www.mdpi.com/2072-6694/16/7/1418

Internet

https://www.mdpi.com/2072-6694/16/7/1418

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