Purinergic System Signaling in Metainflammation-Associated Osteoarthritis

Purinergic System Signaling in Metainflammation-Associated Osteoarthritis

Inflammation triggered by metabolic imbalance, also called metainflammation, is low-grade inflammation caused by the components involved in metabolic syndrome (MetS), including central obesity and impaired glucose tolerance. This phenomenon is mainly due to excess nutrients and energy, and it contri...

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Bibliographic Details
Main Authors: Paula Gratal, Ana Lamuedra, Juan Pablo Medina, Ismael Bermejo-Álvarez, Raquel Largo, Gabriel Herrero-Beaumont, Aránzazu Mediero
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Medicine
Subjects:
purinergic system
A2AR
P2X7 receptor
osteoarthritis
metainflammation
mitochondrial metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00506/full

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https://www.frontiersin.org/article/10.3389/fmed.2020.00506/full

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