Assessing the kinetics of oxygen-unloading from red cells using FlowScore, a flow-cytometric proxy of the functional quality of bloodResearch in context

Assessing the kinetics of oxygen-unloading from red cells using FlowScore, a flow-cytometric proxy of the functional quality of bloodResearch in context

Summary: Background: Metrics evaluating the functional quality of red blood cells (RBCs) must consider their role in oxygen delivery. Whereas oxygen-carrying capacity is routinely reported using haemoglobin assays, the rate of oxygen exchange is not measured, yet also important for tissue oxygenati...

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Bibliographic Details
Main Authors: Julija Rabcuka, Peter A. Smethurst, Katharina Dammert, Jarob Saker, Gemma Aran, Geraldine M. Walsh, Joanne C.G. Tan, Margarita Codinach, Ken McTaggart, Denese C. Marks, Stephan J.L. Bakker, Amy McMahon, Emanuele Di Angelantonio, David J. Roberts, Slawomir Blonski, Piotr M. Korczyk, Atsushi Shirakami, Rebecca Cardigan, Pawel Swietach
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:EBioMedicine
Subjects:
Haematology
Erythrocytes
Storage lesion
Assay
Oxygen transport
Transfusion
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424005346

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http://www.sciencedirect.com/science/article/pii/S2352396424005346

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