Tuning the fluidity and protein corona of ultrasound-responsive liposomal nanovaccines to program T cell immunity in mice

Abstract Inducing high levels of antigen-specific CD8α+ T cells in the tumor is beneficial for cancer immunotherapy, but achieving this in a safe and effective manner remains challenging. Here, we have developed a designer liposomal nanovaccine containing a sonosensitizer (LNVS) to efficiently progr...

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Bibliographic Details
Main Authors: Jia He, Chaoyu Wang, Xiao Fang, Junyao Li, Xueying Shen, Junxia Zhang, Cheng Peng, Hongjian Li, Sai Li, Jeffrey M. Karp, Rui Kuai
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52104-z