Characterization of Escherichia coli harboring colibactin genes (clb) isolated from beef production and processing systems

Abstract Certain strains of Escherichia coli possess and express the toxin colibactin (Clb) which induces host mutations identical to the signature mutations of colorectal cancer (CRC) that lead to tumorigenic lesions. Since cattle are a known reservoir of several Enterobacteriaceae including E. col...

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Bibliographic Details
Main Authors: Manita Guragain, John W. Schmidt, Norasak Kalchayanand, Aaron M. Dickey, Joseph M. Bosilevac
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09274-x