Effects of methionine deficiency on B7H3-DAP12-CAR-T cells in the treatment of lung squamous cell carcinoma

Abstract Lung squamous cell carcinoma (LUSC) is a subtype of lung cancer for which precision therapy is lacking. Chimeric antigen receptor T-cells (CAR-T) have the potential to eliminate cancer cells by targeting specific antigens. However, the tumor microenvironment (TME), characterized by abnormal...

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Bibliographic Details
Main Authors: Tao Yu, Feng-Qi Nie, Qi Zhang, Shao-Kun Yu, Mei-Ling Zhang, Qian Wang, En-Xiu Wang, Kai-Hua Lu, Ming Sun
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06376-w