Interferon gamma immunoPET imaging to evaluate response to immune checkpoint inhibitors

Interferon gamma immunoPET imaging to evaluate response to immune checkpoint inhibitors

IntroductionWe previously developed a 89Zr-labeled antibody-based immuno-positron emission tomography (immunoPET) tracer targeting interferon gamma (IFNγ), a cytokine produced predominantly by activated T and natural killer (NK) cells during pathogen clearance, anti-tumor immunity, and various infla...

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Bibliographic Details
Main Authors: Justin B. Hackett, Nicholas Ramos, Stephen Barr, Madeline Bross, Nerissa T. Viola, Heather M. Gibson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Oncology
Subjects:
interferon gamma
immunoPET imaging
immunotherapy
immune checkpoint inhibitors
radioactive tracer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1285117/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1285117/full

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