Single nucleotide variants in nuclear pore complex disassembly pathway associated with poor survival in osteosarcoma

Introduction:The bone tumor, osteosarcoma, remains challenging to treat in children and young adults, especially when patients present with metastatic disease. Developing new therapies based on genomic data from sequencing projects has proven difficult given the lack of recurrent genetic lesions acr...

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Bibliographic Details
Main Authors: James E. Jacobs, Lara Davis, Shannon McWeeney
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1303404/full