Optogenetic ion pumps differ with respect to the secondary pattern of K+ redistribution

Abstract We recently reported that strong activation of the optogenetic chloride pump, halorhodopsin leads to a secondary redistribution of K+ ions into the cell, through tonically open, “leak” K+ channels. Here we show that this effect is not unique to halorhodopsin but is also seen with activation...

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Bibliographic Details
Main Authors: R. Ryley Parrish, Tom Jackson‐Taylor, Juha Voipio, Andrew J. Trevelyan
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15778