N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis

N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis

Abstract Background In vitro chondrogenesis depends on the concerted action of numerous signalling pathways, many of which are sensitive to the changes of intracellular Ca2+ concentration. N-methyl-D-aspartate (NMDA) glutamate receptor is a cation channel with high permeability for Ca2+. Whilst ther...

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Bibliographic Details
Main Authors: Csaba Matta, Tamás Juhász, János Fodor, Tibor Hajdú, Éva Katona, Csilla Szűcs-Somogyi, Roland Takács, Judit Vágó, Tamás Oláh, Ádám Bartók, Zoltan Varga, Gyorgy Panyi, László Csernoch, Róza Zákány
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cell Communication and Signaling
Subjects:
Chondrogenesis
Chondrocyte
N-methyl-D-aspartate receptor
NMDAR
siRNA
Single cell calcium imaging
Online Access:https://doi.org/10.1186/s12964-019-0487-3

Internet

https://doi.org/10.1186/s12964-019-0487-3

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