Protective immunity against toxoplasmosis in mice induced by single-dose immunization with rSAG1/2 protein released from poly(lactide-co-glycolide) microparticles

Protective immunity against toxoplasmosis in mice induced by single-dose immunization with rSAG1/2 protein released from poly(lactide-co-glycolide) microparticles

Triphasic sustained release of tachyzoite chimeric protein, rSAG1/2, from poly(lactide-co-glycolide) (PLG)-encapsulated rSAG1/2 (PLG-rSAG1/2) microparticles (MPs) is a promising characteristic for developing a single-dose vaccine against Toxoplasma gondii in domestic animals. In the present study, w...

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Bibliographic Details
Main Authors: Chuang Shu-Chun, Chung Yao-Chi, Yang Chung-Da
Format: Article
Language:English
Published: EDP Sciences 2017-01-01
Series:Parasite
Subjects:
Toxoplasma gondii
Single-dose vaccine
rSAG1/2
Synthetic adjuvant
Poly(lactide-co-glycolide)
Microparticles
Online Access:https://doi.org/10.1051/parasite/2017004

Internet

https://doi.org/10.1051/parasite/2017004

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