One-Step Assembly of a PRRSV Infectious cDNA Clone and a Convenient CRISPR/Cas9-Based Gene-Editing Technology for Manipulation of PRRSV Genome

Porcine reproductive and respiratory syndrome (PRRS) has been a persistent challenge for the swine industry for over three decades due to the lack of effective treatments and vaccines. Reverse genetics systems have been extensively employed to build rapid drug screening platforms and develop genetic...

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Bibliographic Details
Main Authors: Hejin Zhang, Kaiqi Duan, Yingbin Du, Shaobo Xiao, Liurong Fang, Yanrong Zhou
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/9/1816