Adenovirus Encoded Adjuvant (AdEnA) anti-CTLA-4, a novel strategy to improve Adenovirus based vaccines against infectious diseases and cancer

Adenovirus Encoded Adjuvant (AdEnA) anti-CTLA-4, a novel strategy to improve Adenovirus based vaccines against infectious diseases and cancer

IntroductionVirus vectored genetic vaccines (Vvgv) represent a promising approach for eliciting immune protection against infectious diseases and cancer. However, at variance with classical vaccines to date, no adjuvant has been combined with clinically approved genetic vaccines, possibly due to the...

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Bibliographic Details
Main Authors: Anna Morena D’Alise, Linda Nocchi, Irene Garzia, Laura Seclì, Luigia Infante, Fulvia Troise, Gabriella Cotugno, Simona Allocca, Giuseppina Romano, Armin Lahm, Guido Leoni, Emanuele Sasso, Elisa Scarselli, Alfredo Nicosia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
vaccine
genetic adjuvants
immune response
cancer
infectious disease
neoantigens
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1156714/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1156714/full

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