Procyanidin B2 induces apoptosis and autophagy in gastric cancer cells by inhibiting Akt/mTOR signaling pathway

Procyanidin B2 induces apoptosis and autophagy in gastric cancer cells by inhibiting Akt/mTOR signaling pathway

Abstract Background Procyanidin B2 (PB2), a unique component of the grape seed and other medicinal plants. PB2 has shown wide anticancer activity in various human cancer cells. However, it remains unclear about the biological effects and associated mechanisms of PB2 on gastric cancer cells. Methods...

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Bibliographic Details
Main Authors: Yuqin Li, Xiaolan Lu, Peiying Tian, Kai Wang, Jianping Shi
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Gastric cancer
Procyanidin B2
Apoptosis
Autophagy
Akt
mTOR
Online Access:https://doi.org/10.1186/s12906-021-03225-1

Internet

https://doi.org/10.1186/s12906-021-03225-1

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