Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development

Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development

Late onset of clinical symptoms in hepatocellular carcinoma (HCC) results in late diagnosis and poor disease outcome. Approximately 85% of individuals with HCC have underlying liver cirrhosis. However, not all cirrhotic patients develop cancer. Reliable tools that would distinguish cirrhotic patient...

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Bibliographic Details
Main Authors: Katarzyna Lubecka, Kirsty Flower, Megan Beetch, Jay Qiu, Lucinda Kurzava, Hannah Buvala, Adam Ruhayel, Samer Gawrieh, Suthat Liangpunsakul, Tracy Gonzalez, George McCabe, Naga Chalasani, James M Flanagan, Barbara Stefanska
Format: Article
Language:English
Published: Taylor & Francis Group 2018-06-01
Series:Epigenetics
Subjects:
dna methylation
hcc
early detection
cirrhotic populations
Online Access:http://dx.doi.org/10.1080/15592294.2018.1481706

Internet

http://dx.doi.org/10.1080/15592294.2018.1481706

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