Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array

Abstract Biomaterial-based tissue culture platforms have emerged as useful tools to mimic in vivo physiological microenvironments in experimental cell biology and clinical studies. We describe herein a three-dimensional (3D) tissue culture platform using a polydimethylsiloxane (PDMS)-based hanging d...

Full description

Bibliographic Details
Main Authors: Ching-Te Kuo, Jong-Yueh Wang, Yu-Fen Lin, Andrew M. Wo, Benjamin P. C. Chen, Hsinyu Lee
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04718-1