A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy

A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy

Abstract Background While preeclampsia (PE) is a leading cause of pregnancy-related morbidity/mortality, its underlying mechanisms are not fully understood. DNA methylation (DNAm) is a dynamic regulator of gene expression that may offer insight into PE pathophysiology and/or serve as a biomarker (e....

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Bibliographic Details
Main Authors: Shuwei Liu, Haoyi Fu, Mitali Ray, Lacey W. Heinsberg, Yvette P. Conley, Cindy M. Anderson, Carl A. Hubel, James M. Roberts, Arun Jeyabalan, Daniel E. Weeks, Mandy J. Schmella
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Epigenetics Communications
Subjects:
Preeclampsia
Pre-eclampsia
DNA methylation
Epigenetics
Hypertensive disorder of pregnancy
Surrogate variable analysis
Online Access:https://doi.org/10.1186/s43682-022-00014-w

Internet

https://doi.org/10.1186/s43682-022-00014-w

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