Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects

Abstract Acute coronary syndromes, such as myocardial infarction (MI), lack effective therapies beyond heart transplantation, which is often hindered by donor scarcity and postoperative complications. Human induced pluripotent stem cells (hiPSCs) offer the possibility of myocardial regeneration by d...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Xi Jiang, Xin Lian, Kun Wei, Jie Zhang, Kaihua Yu, Haoming Li, Haichun Ma, Yin Cai, Lei Pang
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	BMC 2024-10-01
Sraith:	Stem Cell Research & Therapy
Ábhair:	Acute coronary syndromes Myocardial infarction Induced pluripotent stem cells iPSC-cardiomyocytes Maturation Energy metabolism
Rochtain ar líne:	https://doi.org/10.1186/s13287-024-03961-4

Míreanna comhchosúla

Maturation of induced pluripotent stem cell-derived cardiomyocytes and its therapeutic effect on myocardial infarction in mouse
de réir: Peng Wu, et al.
Foilsithe / Cruthaithe: (2023-02-01)

Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling
de réir: Sofija Vučković, et al.
Foilsithe / Cruthaithe: (2022-07-01)

iPSC-Derived Cardiomyocytes in Inherited Cardiac Arrhythmias: Pathomechanistic Discovery and Drug Development
de réir: Eline Simons, et al.
Foilsithe / Cruthaithe: (2023-01-01)

Modeling hypertrophic cardiomyopathy with human cardiomyocytes derived from induced pluripotent stem cells
de réir: Jiangtao Li, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Metabolic Maturation Exaggerates Abnormal Calcium Handling in a <i>Lamp2</i> Knockout Human Pluripotent Stem Cell-Derived Cardiomyocyte Model of Danon Disease
de réir: Robert J. Barndt, et al.
Foilsithe / Cruthaithe: (2022-12-01)

Disease Modeling of Mitochondrial Cardiomyopathy Using Patient-Specific Induced Pluripotent Stem Cells
de réir: Takeshi Tokuyama, et al.
Foilsithe / Cruthaithe: (2021-09-01)

Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes
de réir: Francis Grafton, et al.
Foilsithe / Cruthaithe: (2021-08-01)

Cardiac repair in a murine model of myocardial infarction with human induced pluripotent stem cell-derived cardiomyocytes
de réir: Xin Jiang, et al.
Foilsithe / Cruthaithe: (2020-07-01)

Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
de réir: Liang Ye, et al.
Foilsithe / Cruthaithe: (2021-03-01)

Action potential variability in human pluripotent stem cell-derived cardiomyocytes obtained from healthy donors
de réir: A. B. Carvalho, et al.
Foilsithe / Cruthaithe: (2022-12-01)

The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes
de réir: Xiaoou Li, et al.
Foilsithe / Cruthaithe: (2024-10-01)

Strategies to improve the therapeutic effect of pluripotent stem cell-derived cardiomyocytes on myocardial infarction
de réir: Yang Xiao, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Overexpression of KCNJ2 enhances maturation of human-induced pluripotent stem cell-derived cardiomyocytes
de réir: Jingjun Zhou, et al.
Foilsithe / Cruthaithe: (2023-04-01)

Qualitative transcriptional signatures for evaluating the maturity degree of pluripotent stem cell-derived cardiomyocytes
de réir: Rou Chen, et al.
Foilsithe / Cruthaithe: (2019-03-01)

Immune cells and RBCs derived from human induced pluripotent stem cells: method, progress, prospective challenges
de réir: Jin-he Jiang, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Impaired Relaxation in Induced Pluripotent Stem Cell‐Derived Cardiomyocytes with Pathogenic TNNI3 Mutation of Pediatric Restrictive Cardiomyopathy
de réir: Renjie Wang, et al.
Foilsithe / Cruthaithe: (2024-03-01)

Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
de réir: Guillaume Gilbert, et al.
Foilsithe / Cruthaithe: (2021-11-01)

Rock inhibitor may compromise human induced pluripotent stem cells for cardiac differentiation in 3D
de réir: Bin Jiang, et al.
Foilsithe / Cruthaithe: (2022-03-01)

Unlocking the Pragmatic Potential of Regenerative Therapies in Heart Failure with Next-Generation Treatments
de réir: Yoshikazu Kishino, et al.
Foilsithe / Cruthaithe: (2023-03-01)

In vitro maturation of human pluripotent stem cell-derived cardiomyocyte: A promising approach for cell therapy
de réir: Yun-Gwi Park, et al.
Foilsithe / Cruthaithe: (2022-06-01)

In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts
de réir: Shin Kadota, et al.
Foilsithe / Cruthaithe: (2017-02-01)

ELM2‐SANT Domain‐Containing Scaffolding Protein 1 Regulates Differentiation and Maturation of Cardiomyocytes Derived From Human‐Induced Pluripotent Stem Cells
de réir: Yu‐An Lu, et al.
Foilsithe / Cruthaithe: (2024-07-01)

Fatty Acid-Treated Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes Exhibit Adult Cardiomyocyte-Like Energy Metabolism Phenotypes
de réir: Yuichi Horikoshi, et al.
Foilsithe / Cruthaithe: (2019-09-01)

Genetic and Pharmacological YAP Activation Induces Proliferation and Improves Survival in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
de réir: Thuy Anh Bui, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Recent advances in regulating the proliferation or maturation of human-induced pluripotent stem cell-derived cardiomyocytes
de réir: Hao Yang, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Temporal Control of the WNT Signaling Pathway During Cardiac Differentiation Impacts Upon the Maturation State of Human Pluripotent Stem Cell Derived Cardiomyocytes
de réir: Chantelle Tsoi, et al.
Foilsithe / Cruthaithe: (2022-03-01)

Generation of an Alagille syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi032-A) carrying a heterozygous mutation (p.Cys682Leufs*7) in the JAG1 gene
de réir: Omer Hatim, et al.
Foilsithe / Cruthaithe: (2023-12-01)

Alzheimer’s in a dish – induced pluripotent stem cell-based disease modeling
de réir: Sherida de Leeuw, et al.
Foilsithe / Cruthaithe: (2019-07-01)

Follistatin-like 1 promotes proliferation of matured human hypoxic iPSC-cardiomyocytes and is secreted by cardiac fibroblasts
de réir: Marijn C. Peters, et al.
Foilsithe / Cruthaithe: (2022-06-01)

iPSC-Derived Cardiomyocytes as a Disease Model to Understand the Biology of Congenital Heart Defects
de réir: Chithra K. Pushpan, et al.
Foilsithe / Cruthaithe: (2024-08-01)

Impact of Neurons on Patient-Derived Cardiomyocytes Using Organ-On-A-Chip and iPSC Biotechnologies
de réir: Albin A. Bernardin, et al.
Foilsithe / Cruthaithe: (2022-11-01)

Three-dimensional cardiac organoid formation accelerates the functional maturation of human induced pluripotent stem cell-derived cardiomyocytes
de réir: Hanbyeol Lee, et al.
Foilsithe / Cruthaithe: (2022-05-01)

Sarcomere Disassembly and Transfection Efficiency in Proliferating Human iPSC-Derived Cardiomyocytes
de réir: Qianliang Yuan, et al.
Foilsithe / Cruthaithe: (2022-01-01)

How can we use stem cell-derived cardiomyocytes to understand the involvement of energetic metabolism in alterations of cardiac function?
de réir: Sabine Rebs, et al.
Foilsithe / Cruthaithe: (2023-09-01)

Do Human iPSC-Derived Cardiomyocytes Cultured on PLA Scaffolds Induce Expression of CD28/CTLA-4 by T Lymphocytes?
de réir: David Sergeevichev, et al.
Foilsithe / Cruthaithe: (2022-01-01)

Co-transplantation of Mesenchymal Stromal Cells and Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improves Cardiac Function After Myocardial Damage
de réir: Klaus Neef, et al.
Foilsithe / Cruthaithe: (2022-01-01)

Increasing the physical size and nucleation status of human pluripotent stem cell-derived ventricular cardiomyocytes by cell fusion
de réir: Chi-Wing Kong, et al.
Foilsithe / Cruthaithe: (2017-03-01)

Polymerized Laminin-521: A Feasible Substrate for Expanding Induced Pluripotent Stem Cells at a Low Protein Concentration
de réir: Fernanda C. P. Mesquita, et al.
Foilsithe / Cruthaithe: (2022-12-01)

Three-Dimensional Poly-(ε-Caprolactone) Nanofibrous Scaffolds Promote the Maturation of Human Pluripotent Stem Cells-Induced Cardiomyocytes
de réir: Mingming Zhang, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Generation of two induced pluripotent stem cell lines from patients with cardiac amyloidosis carrying heterozygous transthyretin (TTR) mutation
de réir: Bernardo Bonilauri, et al.
Foilsithe / Cruthaithe: (2023-10-01)