In Vitro Study of Extracellular Vesicles Migration in Cartilage-Derived Osteoarthritis Samples Using Real-Time Quantitative Multimodal Nonlinear Optics Imaging

In Vitro Study of Extracellular Vesicles Migration in Cartilage-Derived Osteoarthritis Samples Using Real-Time Quantitative Multimodal Nonlinear Optics Imaging

Mesenchymal stromal cells (MSCs)-derived extracellular vesicles (EVs) are promising therapeutic nano-carriers for the treatment of osteoarthritis (OA). The assessment of their uptake in tissues is mandatory but, to date, available technology does not allow to track and quantify incorporation in real...

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Bibliographic Details
Main Authors: Leonardo Mortati, Laura de Girolamo, Carlotta Perucca Orfei, Marco Viganò, Marco Brayda-Bruno, Enrico Ragni, Alessandra Colombini
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceutics
Subjects:
osteoarthritis
cartilage
mesenchymal stem cells
extracellular vesicles
coherent anti-stokes raman scattering
second harmonic generation
Online Access:https://www.mdpi.com/1999-4923/12/8/734

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https://www.mdpi.com/1999-4923/12/8/734

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