Mutually Dependent Clustering of SynDIG4/PRRT1 and AMPA Receptor Subunits GluA1 and GluA2 in Heterologous Cells and Primary Neurons

Mutually Dependent Clustering of SynDIG4/PRRT1 and AMPA Receptor Subunits GluA1 and GluA2 in Heterologous Cells and Primary Neurons

Regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors (AMPARs) at synapses is a predominant mechanism for regulating synaptic strength. We identified the transmembrane protein synapse differentiation-induced gene 1 (SynDIG1; SD1) as an AMPAR interacting p...

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Bibliographic Details
Main Authors: Kristopher E. Plambeck, Chun-Wei He, Hector H. Navarro, Elva Díaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
AMPA receptor (AMPAR)
SynDIG4
PRRT1
SynDIG1
synaptic plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.788620/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.788620/full

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