Nonviral delivery systems for antisense oligonucleotide therapeutics

Abstract Antisense oligonucleotides (ASOs) are an important tool for the treatment of many genetic disorders. However, similar to other gene drugs, vectors are often required to protect them from degradation and clearance, and to accomplish their transport in vivo. Compared with viral vectors, artif...

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Bibliographic Details
Main Authors: Si Huang, Xin-Yan Hao, Yong-Jiang Li, Jun‑Yong Wu, Da-Xiong Xiang, Shilin Luo
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-09-01
Series:Biomaterials Research
Subjects:
Online Access:https://doi.org/10.1186/s40824-022-00292-4