Placode and neural crest origins of congenital deafness in mouse models of Waardenburg-Shah syndrome

Summary: Mutations in the human genes encoding the endothelin ligand-receptor pair EDN3 and EDNRB cause Waardenburg-Shah syndrome (WS4), which includes congenital hearing impairment. The current explanation for auditory dysfunction is defective migration of neural crest-derived melanocytes to the in...

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Detalhes bibliográficos
Principais autores: Jaime Tan, Alicia Duron, Henry M. Sucov, Takako Makita
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2025-01-01
coleção:iScience
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004224029079