Analysis of innate and acquired resistance to anti-CD20 antibodies in malignant and nonmalignant B cells
The anti-CD20 monoclonal antibody, rituximab, provides a significant therapeutic benefit for patients with B-cell disorders. However, response to therapy varies and relapses are common, so an understanding of both inherited and acquired rituximab resistance is needed. In order to identify mechanisms...
Main Authors: | George W. Small, Howard L. McLeod, Kristy L. Richards |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2013-02-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/31.pdf |
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