Somatic Mutational Profile of High-Grade Serous Ovarian Carcinoma and Triple-Negative Breast Carcinoma in Young and Elderly Patients: Similarities and Divergences

Somatic Mutational Profile of High-Grade Serous Ovarian Carcinoma and Triple-Negative Breast Carcinoma in Young and Elderly Patients: Similarities and Divergences

Background: Triple-negative breast cancer (TNBC) and High-Grade Serous Ovarian Cancer (HGSOC) are aggressive malignancies that share similarities; however, different ages of onset may reflect distinct tumor behaviors. Thus, our aim was to compare somatic mutations in potential driver genes in 109 TN...

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Bibliographic Details
Main Authors: Pedro Adolpho de Menezes Pacheco Serio, Gláucia Fernanda de Lima Pereira, Maria Lucia Hirata Katayama, Rosimeire Aparecida Roela, Simone Maistro, Maria Aparecida Azevedo Koike Folgueira
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
triple-negative breast cancer
high-grade serous ovarian carcinoma
somatic
young adult
Online Access:https://www.mdpi.com/2073-4409/10/12/3586

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https://www.mdpi.com/2073-4409/10/12/3586

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