Selective blocking of clathrin-mediated endocytosis by RNA interference: epsin as target protein

Epsin is an essential accessory protein exclusively implicated in clathrin-mediated endocytosis and therefore an ideal target to study involvement of this entry route in the uptake of bioligands. The technique of RNA interference (RNAi) was exploited to generate a cell line constitutively silencing...

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Bibliographic Details
Main Authors: Davy Vanden Broeck, Marc J.S. De Wolf
Format: Article
Language:English
Published: Taylor & Francis Group 2006-10-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/000112265