Corilagin Alleviates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced C57BL/6 Mice by Ameliorating Oxidative Stress and Restoring Autophagic Flux

Corilagin Alleviates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced C57BL/6 Mice by Ameliorating Oxidative Stress and Restoring Autophagic Flux

Corilagin (Cori) possesses multiple biological activities. To determine whether Cori can exert protective effects against nonalcoholic fatty liver disease (NAFLD) and its potential mechanisms. C57BL/6 mice were fed with high-fat diet (HFD) alone or in combination with Cori (20 mg/kg, i.p.) and AML12...

Full description

Bibliographic Details
Main Authors: Rong Zhang, Kexin Chu, Nengjiang Zhao, Jingjing Wu, Lina Ma, Chenfang Zhu, Xia Chen, Gang Wei, Mingjuan Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
Corilagin
nonalcoholic fatty liver disease
autophagy
oxidative stress
mitochondrial dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01693/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01693/full

Similar Items