Early life sleep disruption potentiates lasting sex-specific changes in behavior in genetically vulnerable Shank3 heterozygous autism model mice

Early life sleep disruption potentiates lasting sex-specific changes in behavior in genetically vulnerable Shank3 heterozygous autism model mice

Abstract Background Patients with autism spectrum disorder (ASD) experience high rates of sleep disruption beginning early in life; however, the developmental consequences of this disruption are not understood. We examined sleep behavior and the consequences of sleep disruption in developing mice be...

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Bibliographic Details
Main Authors: Julia S. Lord, Sean M. Gay, Kathryn M. Harper, Viktoriya D. Nikolova, Kirsten M. Smith, Sheryl S. Moy, Graham H. Diering
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Molecular Autism
Subjects:
Sleep
Autism spectrum disorder
Shank3
Social behavior
Brain development
Online Access:https://doi.org/10.1186/s13229-022-00514-5

Internet

https://doi.org/10.1186/s13229-022-00514-5

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